New York Times 11 February: "Mice Fall Short as Test Subjects for Humans' Deadly Ills"
"For decades, mice have been the species of choice in the study of human diseases. But now, researchers report evidence that the mouse model has been totally misleading for at least three major killers - sepsis, burns and trauma. As a result, years and billions of dollars have been wasted following false leads, they say."
"They are so ingrained in trying to cure mice that they forget we are trying to cure humans."
"It argues strongly - go to the patients. Get their cells. Get their tissues whenever you can."
New Scientist 15 December: “How human biology can prevent drug deaths”
“It is a tragedy that so many suffer or die through the use of inadequately tested drugs when tests based on human biology are readily available. Yet governments continue to mandate animal tests, despite the lack of a formal demonstration of fitness for purpose, and a growing global realisation among scientists that animal toxicity tests are inadequate and must be replaced.” See more...