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Newsletter Autumn 2008 available now

Read our latest newsletter here (pdf)


BBC admits bias but defends lies

See no facts, hear no facts, speak no facts.
‘See no facts, hear no facts, speak no facts.’

15 October 2008: BBC Trust (the BBC's watchdog) upholds BBC ruling that animal testing documentary 'Monkeys, Rats and Me' was unbalanced. Yet they still deny the programme was inaccurate, ignoring conclusive evidence to the contrary.

Read more here

See our original complaints, the BBC's original response, our appeal and the BBC's ruling, the programme maker's comments and Professor Page's letter


Mouse models for neurological disease "nearly useless"

Read more here


 

Systematic reviews of animal experiments demonstrate poor contributions toward human healthcare

New study published in Reviews on Recent Clinical Trials 2008; 3(2): 89-96

In 20 published systematic reviews, animal models demonstrated significant potential to contribute toward the development of clinical interventions in only two cases, one of which was contentious. Seven additional reviews failed to demonstrate utility in reliably predicting human toxicological outcomes such as carcinogenicity and teratogenicity. Results in animal models were frequently equivocal, or inconsistent with human outcomes. Consequently, animal data may not generally be considered useful for these purposes.

Read the paper here


Studies in dogs and monkeys no more informative than tossing a coin

The common claim that 'virtually every medical achievement of the last century has benefitted to some extent from animal research' is an outrageous abuse of the trust placed by the public in our most prestigious academic institutions, according to science journalist Robert Matthews: see BBC Focus Magazine article (February 2008)

Robert Matthews has re-analysed the data from a much quoted published paper assessing the predictivity of dogs and monkeys for the toxicity of anti-cancer drugs and found that the predictive values quoted were calculated incorrectly. When calculated correctly, "the data provide no statistically credible evidence that these animal models contribute any predictive value, either separately or in combination." This stunning piece of work is published in the February issue of the Journal of the Royal Society of Medicine, for which a subscription is required to view the article.

Robert Matthews has also published an article (subscription required) in the 16 February issue of New Scientist, in which he observes: "Few [studies] provide enough data to allow the value of animal studies to be worked out; those that do suggest they are no more informative than tossing a coin."


ASA rejects claim by Pro-Test that animal testing has been scientifically evaluated

See Pro-Test complaint and ASA adjudication
See article in Daily Express


EMP and EMP Trust letter published in prestigious scientific journal EMBO (European Molecular Biology Organization) Reports


"Tests on mice, rats, rabbits and guinea pigs to stop harmful chemicals reaching humans were once a necessary evil. But such checks now seem embarrassingly old-fashioned..."

Read article in Chemistry World, August 2007


US National Research Council calls for the replacement of animal toxicity tests with superior human based tests.


BBC apologises for unbalanced animal testing documentary ‘Monkeys, Rats and Me’

See our complaints and the BBC's response


Study casts doubt on efficacy of chimpanzee research   Study casts doubt on efficacy of chimpanzee research


Debate at the London School of Economics and Political Science (LSE), January 16th 2007: Animal Testing: Necessary Cruelty or Cruelly Unnecessary?


YOU CAN LISTEN TO THE SPEAKERS HERE: 

Debate at the London School of Economics and Political Science (LSE), January 16th 2007: Animal Testing: Necessary Cruelty or Cruelly Unnecessary?Iain Simpson, Press Officer, Pro-Test Campaign

Dr. Margaret Clotworthy, Safer Medicines Trust

Professor John Stein, Oxford University

Kathy Archibald, Safer Medicines Trust

Thanks to Aled Fisher, Environment and Ethics Officer, LSE Students' Union, for organising and chairing the debate.


EMP supporter Marius Maxwell MBBChir, DPhil - a Cambridge/Oxford/Harvard educated neurosurgeon and neuroscientist speaks out against animal testing.


Europeans for Medical Progress complains to BBC regarding BBC2 programme ‘Monkeys, Rats and Me’.

See our complaints here.


WEATHERALL REPORT ON PRIMATE RESEARCH A CHARADE


EDM 92 'ANIMAL TESTING OF DRUGS'

A phenomenal 250 MPs - a clear majority of those eligible to do so - signed Early Day Motion 92:

"That this House, in common with Europeans for Medical Progress, expresses its concerns regarding the safeguarding of public health through data obtained from laboratory animals, particularly in light of large numbers of serious and fatal adverse drug reactions that were not predicted by animal studies; is concerned that the Government has not commissioned or evaluated any formal research on the efficacy of animal experiments, and has no plans to do so; and, in common with 83 per cent of general practitioners in a recent survey, calls upon the Government to facilitate an independent and transparent scientific evaluation of the use of animals as surrogate humans in drug safety testing and medical research."

You can view the signatories here. You can find the name of your MP here.

This gives the Government a very clear signal that they are in a minority in their reluctance to sanction the evaluation of animal tests that the overwhelming majority of doctors, politicians and the public recognise is necessary. Such a high level of parliamentary endorsement will help us to exert pressure on the Government to start listening to the rational, scientific case for a comparison of animal tests with a battery of state-of-the-art methods of predicting drug safety. These include microdosing, human DNA chips, virtual human organs and tests involving human tissue - which would have predicted the devastating effects of both Vioxx and the Northwick Park drug and could have averted both disasters.

Many thanks to everyone who encouraged their MP to sign in support of such a momentous evaluation. Despite such impressive support, our work is not over yet as the Government still remains to be convinced. Please help us in our efforts to convince them:

To add your support to the call for an independent scientific evaluation of animal experimentation - click here

To print off a petition to gather more support for an independent scientific evaluation of animal experimentation - click here

To read a brief summary of the compelling case for an evaluation - click here


Vivisection is not a reliable means of testing human drugs, writes Kathy Archibald in the Oxford Student Newspaper
Friday June 9th, 2006


Press release 5th June 2006: New booklet proclaiming the benefits of primate research makes insupportable claims

Read more


Europeans for Medical Progress wins university debate with Pro-Test

Science director of EMP, Dr Jarrod Bailey debated Kristina Cook of Pro-Test in front of an audience of over 100 people at Sheffield University Debating Society on May 17th. Dr Bailey presented overwhelming evidence of harm resulting from animal experimentation, as well as outlining the superior methods available today. Just as in a debate between Dr Bailey and Iain Simpson in the House of Commons on March 15th, Pro-Test provided no evidence to support their claims that animal experiments are crucial to medical progress, preferring to continue their attempts to discredit those who disagree with them. However, the audience was not convinced and the motion was carried that: "This house believes that animal testing is detrimental to human health and should be abolished."


It's time to test the testers

Over-reliance on the accuracy of animal testing is dangerously misleading and puts human life at risk, writes Kathy Archibald
Friday May 5, 2006


New paper on primate research published in the December issue of the journal Biogenic Amines:

Non-human primates in medical research and drug development: a critical review

Biogenic Amines, Vol. 19, No. 4-6, pp. 235-255 (2005) Copies available from EMP for £3, including p&p

VSP 2005. Also available online - www.vsppub.com

There is much current debate surrounding the use of non-human primates (NHPs) in medical research and drug development. This review, stimulated by calls for evidence from UK-based inquiries into NHP research, takes a critical view in order to provide some important balance against papers supporting NHP research and calling for it to be expanded. We show that there is a paucity of evidence to demonstrate the positive contribution or successful translation of NHP research to human medicine, that there is a great deal of often overlooked data showing NHP research to be irrelevant, unnecessary, even hazardous to human health and to have little or no predictive value or application to human medicine. We briefly discuss the reasons why this may be so, reflect upon the consequences for future medical progress and, on the basis of our findings, suggest a more scientifically robust and promising way forward.

For the benefit of human medical progress, it is surely time for objectivity, transparency and honesty in the assessment of NHP models and their contribution to medical science. Only by ensuring this can we be confident that we are utilizing scientific technology to the full, performing the best translational research possible, and making real progress towards the relief of human suffering and disease. Read more (pdf)


Animal tests yield misleading results: Education and debate in BMJ USA

Are animal experiments really predictive of human carcinogenicity? Analysis and comment by Andrew Knight, Jarrod Bailey and Jonathan Balcombe, with rebuttal by William H Farland, Bruce Rodan and Peter Preuss, US Environmental Protection Agency, Washington, DC.
Read more...


Fifth World Congress on Alternatives and Animal Use in the Life Sciences

At the end of August, almost 1000 people attended the 'Fifth World Congress on Alternatives and Animal Use in the Life Sciences' in Berlin, the majority of whom were scientists. The presentation of a study invalidating animal-based testing of potential human carcinogens, co-authored by our Science Director Dr Jarrod Bailey, won one of only two conference prizes for its scientific merit, beating off competition from 350 others. Dr Bailey was also invited to present his study on the futility of animal testing for substances that can cause birth defects, which was very well received.
Read more...


PRESS RELEASE - WEDNESDAY 24th AUGUST 2005

ANIMAL TESTING - MPs, GPs and scientists demand evaluation

The RDS' claims about the medical value of animal experimentation are unsubstantiated by scientific evidence. Europeans for Medical Progress has amassed overwhelming evidence, from the scientific literature, of harm to humans caused by reliance on misleading animal tests.
Read more...


Europeans for Medical Progress submits evidence to primate study

Europeans for Medical Progress, together with Antidote-Europe, has submitted evidence to a working group set up by The Academy of Medical Sciences, the Royal Society, the Medical Research Council and the Wellcome Trust to examine the recent, current and future scientific basis for biological and medical research involving non-human primates. As we state in our submission, we welcome this inquiry, though with reservations that it is being overseen by four organisations which actively promote and defend NHP research.
Read our submission here (pdf)

We have also submitted comments to the Home Office on the Animal Procedures Committee Report on the use of non-human primates under the Animal (Scientific Procedures) Act 1986.
Read our submission here (pdf)


Drug and Chemical Tests Using Animals Fail to Predict Birth Defect Risk Half the Time

Pregnant women may unknowingly be putting their unborn children at risk of birth defects by taking over-the-counter medications and prescription drugs, and using common household chemicals, according to a new study published in the May issue of the research journal, Biogenic Amines.
Read more here...


Animal testing - science or fiction?

Given that prescription medicines are the fourth biggest killer in the western world, why hasn't the effectiveness of drug safety testing on animals been subjected to greater scrutiny?

4 page article by Europeans for Medical Progress in the May issue of the Ecologist, available here.


ANIMAL TESTING - MPs, GPs and scientists demand evaluation

Animal tests were made a legal requirement following the Thalidomide tragedy forty years ago, in the hope of preventing another such disaster. But have they lived up to their promise? Recently withdrawn arthritis drug Vioxx was safe and even beneficial to animal's hearts but caused as many as 140,000 heart attacks and strokes in people - the biggest drug catastrophe in history.[1] Shockingly, adverse reactions to prescription medicines (all tested for safety on animals) are now the fourth leading cause of death in the western world: killing over 10,000 people a year in the UK and costing the NHS £466 million.[2] New human-based safety tests before and during clinical trials (such as microdosing) could prevent many of these deaths.
Read more here...


Doctors don't trust animal experiments

We commissioned a survey of 500 GPs opinions on animal experimentation -
Read the full media release

 
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