Reports
Biogenic Amines, Vol. 19, No. 4-6, pp. 235-255
(2005)
VSP 2005. Also available online - www.vsppub.com
There is much current debate surrounding the
use of non-human primates (NHPs) in medical research
and drug development. This review, stimulated
by calls for evidence from UK-based inquiries
into NHP research, takes a critical view in order
to provide some important balance against papers
supporting NHP research and calling for it to
be expanded. We show that there is a paucity
of evidence to demonstrate the positive contribution
or successful translation of NHP research to
human medicine, that there is a great deal of
often overlooked data showing NHP research to
be irrelevant, unnecessary, even hazardous to
human health and to have little or no predictive
value or application to human medicine. We briefly
discuss the reasons why this may be so, reflect
upon the consequences for future medical progress
and, on the basis of our findings, suggest a
more scientifically robust and promising way
forward.
For the benefit of human medical progress, it
is surely time for objectivity, transparency
and honesty in the assessment of NHP models and
their contribution to medical science. Only by
ensuring this can we be confident that we are
utilizing scientific technology to the full,
performing the best translational research possible,
and making real progress towards the relief of
human suffering and disease.
The Future of Teratology Research is In Vitro
Paper published in Biogenic
Amines, vol.19,
N° 2, pp 97-146, May 2005
reporting
on a study of 40 years of teratology (birth defect)
research: lead author Dr Jarrod Bailey, Science
Director of Europeans for Medical Progress.
Drug and Chemical Tests Using Animals Fail to
Predict Birth Defect Risk Half the Time
Pregnant women may unknowingly be putting their
unborn children at risk of birth defects by taking
over-the-counter medications and prescription
drugs, and using common household chemicals,
according to a new study published in the May
issue of the research journal, Biogenic
Amines.
A Critical Look at Animal Experimentation
A booklet by the Medical Research Modernisation
Committee examining the impact of animal experimentation
on research into cancer, AIDS, nerological disorders
and others, as well as outlining more valid human-based
methods of research.
Perspectives
A journal
focusing on the use of animals in biomedical
research, published by the Medical Research Modernization
Committee (reproduced with permission)
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